Dhaka Ram Bhandari, Giulia Coliva, Maria Fedorova, Bernhard Spengler “Single Cell Analysis by High-Resolution Atmospheric-Pressure MALDI MS Imaging” Link 

Robbin Bouwmeester, Lennart Martens, Sven Degroeve “Generalized calibration across LC-setups for generic prediction of small molecule retention times” Link 


Gabriele Cruciani, Pedro Domingues, Maria Fedorova, Francesco Galli, Corinne M. Spickett “Redox lipidomics and adductomics – Advanced analytical strategies to study oxidized lipids and lipid-protein adducts” Link 

Elisabete Maciel, Bruno M. Neves, João Martins, Simone Colombo, Maria Teresa Cruz, Pedro Domingues, M. Rosário M. Domingues “Oxidized phosphatidylserine mitigates LPS-triggered macrophage inflammatory status through modulation of JNK and NF-kB signaling cascades” Link 

Bebiana C. Sousa, Tanzim Ahmed, William L. Dann, Jed Ashman, Alexandre Guy, Thierry Durand, Andrew R. Pitt, Corinne M. Spickett “Short-chain lipid peroxidation products form covalent adducts with pyruvate kinase and inhibit its activity in vitro and in breast cancer cells” Link 

C. Martín-Sierra, P. Laranjeira, M.R. Domingues, A. Paiva “Lipoxidation and cancer immunity” Link 

Erica Gianazza, Maura Brioschi, Alma Martinez Fernandez, Cristina Banfi “Lipoxidation in cardiovascular diseases” Link 

Dolores Pérez-Sala, Rosário Domingues “Lipoxidation targets: From basic mechanisms to pathophysiology” Link

Javier-Fernando Montero-Bullon, Tânia Melo, M. Rosário M Domingues, Pedro Domingues “Liquid chromatography/tandem mass spectrometry characterization of nitroso, nitrated and nitroxidized cardiolipin products” Link 

Isabel Campos-Pinto, Lucía Méndez, James Schouten, John Wilkins, Maria Fedorova, Andrew R. Pitt, Paul Davis, Corinne M. Spickett “Epitope mapping and characterization of 4-hydroxy-2-nonenal modified-human serum albumin using two different polyclonal antibodies” Link 

Florian Füssl, Angela Criscuolo, Ken Cook, Kai Scheffler, Jonathan Bones “Cracking Proteoform Complexity of Ovalbumin with Anion-Exchange Chromatography–High-Resolution Mass Spectrometry under Native Conditions” Link 

Javier-Fernando Montero-Bullon, Tânia Melo, Rita Ferreira, Ana Isabel Padrão, Paula A. Oliveira, M. Rosário M. Domingues, Pedro Domingues “Exercise training counteracts urothelial carcinoma-induced alterations in skeletal muscle mitochondria phospholipidome in an animal model” Link

C. Martín-Sierra, R. Martins, P. Laranjeira, M. Coucelo, A.M. Abrantes, R.C. Oliveira, J.G. Tralhão, M.F. Botelho, E. Furtado, M.R. Domingues, A. Paiva “Functional and Phenotypic Characterization of Tumor-Infiltrating Leukocyte Subsets and Their Contribution to the Pathogenesis of Hepatocellular Carcinoma and Cholangiocarcinoma” Link 

Sofia Duarte, Tânia Melo, Rosário Domingues, Juan de Dios Alché, Dolores Pérez-Sala “Insight into the cellular effects of nitrated phospholipids: Evidence for pleiotropic mechanisms of action” Link 

Catarina B. Afonso, Corinne M. Spickett “Lipoproteins as targets and markers of lipoxidation” Link 

Silvia Zorrilla, Andreia Mónico, Sofia Duarte, Germán Rivas, Dolores Pérez-Sala, María A. Pajares “Integrated approaches to unravel the impact of protein lipoxidation on macromolecular interactions” Link

Carmen Martín-Sierra, Ricardo Martins, Paula Laranjeira, A. Margarida Abrantes, R. Caetano Oliveira, J. Guilherme Tralhão, M. Filomena Botelho, Emanuel Furtado, Rosário Domingues, Artur Paiva “Functional Impairment of Circulating FcεRI + Monocytes and Myeloid Dendritic Cells in Hepatocellular Carcinoma and Cholangiocarcinoma Patients” Link 

Alma Martinez Fernandez, Luca Regazzoni, Maura Brioschi, Erica Gianazza, Piergiuseppe Agostoni, Giancarlo Aldini, Cristina Banfi “Pro-oxidant and pro-inflammatory effects of glycated albumin on cardiomyocytes” Link 

Simone Colombo, Angela Criscuolo, Martin Zeller, Maria Fedorova, M. Rosário Domingues, Pedro Domingues “Analysis of oxidised and glycated aminophospholipids: Complete structural characterisation by C30 liquid chromatography-high resolution tandem mass spectrometry” Link 

Zhixu Ni, Bebiana C. Sousa, Simone Colombo, Catarina B. Afonso, Tania Melo, Andrew R. Pitt, Corinne M. Spickett, Pedro Domingues, M. Rosário Domingues, Maria Fedorova, Angela Criscuolo. “Evaluation of air oxidized PAPC: A multi laboratory study by LC-MS/MS” Free Radical Biology and Medicine (2019). link

Zhixu Ni, Laura Goracci, Gabriele Cruciani, Maria Fedorova. “Computational solutions in redox lipidomics – Current strategies and future perspectives.” Free Radical Biology and Medicine (2019). link

Ana S C Silva, Robbin Bouwmeester, Lennart Martens, Sven Degroeve. “Accurate peptide fragmentation predictions allow data driven approaches to replace and improve upon proteomics search engine scoring functions.” Bioinformatics (2019). link

Leanne C. Nye, Jonathan P. Williams, Nyasha C. Munjoma, Marine P.M. Letertre, Muireann Coen, Robbin Bouwmeester, Lennart Martens, Jonathan R. Swann, Jeremy K. Nicholson, Robert S. Plumb, Michael McCullagh, Lee A. Gethings, Steven Lai, James I. Langridge, Johannes P.C. Vissers, Ian D. Wilson. “A Comparison of Collision Cross Section Values Obtained via Travelling Wave Ion Mobility-Mass Spectrometry and Ultra High Performance Liquid Chromatography-Ion Mobility-Mass Spectrometry: Application to the Characterisation of Metabolites in Rat Urine.”  Journal of Chromatography A (2019). link

David L. Marshall, Angela Criscuolo, Reuben S. E. Young, Berwyck L. J. Poad, Martin Zeller, Gavin E. Reid, Todd W. Mitchell, Stephen J. Blanksby. “Mapping Unsaturation in Human Plasma Lipids by Data-Independent Ozone-Induced Dissociation.” Journal of The American Society for Mass Spectrometry (2019). link

Mike Lange, Zhixu Ni, Angela Criscuolo, Maria Fedorova. “Liquid chromatography techniques in lipidomics research.” Chomatographia (2019). link

Angela Criscuolo, Martin Zeller, Ken Cook, Georgia Angelidou, Maria Fedorova. “Rational selection of reverse phase columns for high throughput LC-MS lipidomics.” Chemistry and Physics of Lipids (2019). link

Andreia Mónico, Sofia Duarte, María A. Pajares, Dolores Pérez-Sala. “Vimentin disruption by lipoxidation and electrophiles: Role of the cysteine residue and filament dynamics.” Redox Biology (2019). link

Robbin Bouwmeester, Lennart Martens, Sven Degroeve. “Comprehensive and Empirical Evaluation of Machine Learning Algorithms for Small Molecule LC Retention Time Prediction” Analytical chemistry (2019). Link

Tânia Melo, Javier-Fernando Montero-Bullon, M. Rosário Domingues, and Pedro Domingues. “Discovery of bioactive nitrated lipids and nitro-lipid-protein adducts using mass spectrometry-based approaches” Redox Biology (2019). Link

Giulia Coliva, Sofia Duarte, Dolores Pérez-Sala, and Maria Fedorova. “Impact of inhibition of the autophagy-lysosomal pathway on biomolecules carbonylation and proteome regulation in rat cardiac cells” Redox Biology (2019). Link


Álvaro Viedma-Poyatos, Yolanda de Pablo, Milos Pekny, Dolores Pérez-Sala. “The cysteine residue of glial fibrillary acidic protein is a critical target for lipoxidation and required for efficient network organization.” Link 

Julita Pietrzak, Corinne M. Spickett, Tomasz Płoszaj, László Virág, Agnieszka Robaszkiewicz “PARP1 promoter links cell cycle progression with adaptation to oxidative environment” Link

Marco Mol, Genny Degani, Crescenzo Coppa, Giovanna Baron, Laura Popolo, Marina Carini, Giancarlo Aldini, Giulio Vistoli, Alessandra Altomare. “Advanced lipoxidation end products (ALEs) as RAGE binders: Mass spectrometric and computational studies to explain the reasons why” Redox Biology (2018). Link

Javier-Fernando Montero-Bullon, Tânia Melo, M. Rosário Domingues, and Pedro Domingues. “Characterization of Nitrophospholipid‐Peptide Covalent Adducts by Electrospray Tandem Mass Spectrometry: A First Screening Analysis Using Different Instrumental Platforms” European Journal of Lipid Science and Technology (2018). Link

Simone Colombo, Pedro Domingues, and M. Rosário Domingues. “Mass spectrometry strategies to unveil modified aminophospholipids of biological interest.” Mass Spectrometry Reviews (2018). Link

Simone Colombo, Carmen Martín-Sierra, Tânia Melo, Paula Laranjeira, Artur Paiva, Pedro Domingues, M. Rosário Domingues. “Modulation of the inflammatory response of immune cells in human peripheral blood by oxidized arachidonoyl aminophospholipids” Archives of biochemistry and biophysics (2018). Link

Evelyn Rampler, Angela Criscuolo, Martin Zeller, Yasin El Abiead, Harald Schoeny, Gerrit Hermann, Elena Sokol, Ken Cook, David A. Peake, Bernard Delanghe, and Gunda Koellensperger. “A novel lipidomics workflow for improved human plasma identification and quantification using RPLC-MSn methods and isotope dilution strategies”. Analytical chemistry (2018). Link

Simone Colombo, Tânia Melo, Marta Martínez-López, M. Jesús Carrasco, M. Rosario Domingues, Dolores Pérez-Sala, Pedro Domingues. “Phospholipidome of endothelial cells shows a different adaptation response upon oxidative, glycative and lipoxidative stress”. Scientific Reports (2018). Link

Sofia Duarte, Álvaro Viedma-Poyatos, Elena Navarro-Carrasco, Alma E. Martínez, María A. Pajares, Dolores Pérez-Sala. “Vimentin filaments interact with the mitotic cortex allowing normal cell division” bioRxiv (2018). Link

Catarina B. Afonso, Bebiana C. Sousa, Andrew R. Pitt, Corinne M. Spickett. “A mass spectrometry approach for the identification and localization of small aldehyde modifications of proteins” Archives of Biochemistry and Biophysics (2018). Link

Roberta Baetta, Marta Pontremoli, Alma Martinez Fernandez, Corinne M. Spickett, Cristina Banfi. “Proteomics in cardiovascular diseases: Unveiling sex and gender differences in the era of precision medicine.” Journal of proteomics (2018). Link


Simone Colombo, Giulia Coliva, Agnieszka Kraj, Jean-Pierre Chervet, Maria Fedorova, Pedro Domingues and M. Rosário Domingues. “Electrochemical oxidation of phosphatidylethanolamines studied by mass spectrometry.” Journal of Mass Spectrometry (2017). Link

Andreia Mónico, Eva Martínez-Senra, F. Javier Cañada, Silvia Zorrilla, and Dolores Pérez-Sala. “Drawbacks of Dialysis Procedures for Removal of EDTA.” PloS one (2017), e0169843. Link
Maura Brioschi, Alma Martinez Fernandez & Cristina Banfi. “Exploring the biochemistry of the prenylome and its role in disease through proteomics: progress and potential” Expert Review of Proteomics (2017). Link
The following articles are part of a Special Issue on 4-Hydroxynonenal and Related Lipid Peroxidation Products:

Marco Mol, Luca Regazzoni, Alessandra Altomare, Genny Degani, Marina Carini, Giulio Vistoli, and Giancarlo Aldini. “Enzymatic and Non-Enzymatic Detoxification of 4-Hydroxynonenal: Methodological Aspects and Biological Consequences.” Free Radical Biology and Medicine (2017). Link

Bebiana C. Sousa, Andrew R. Pitt, and Corinne M. Spickett. “Chemistry and analysis of HNE and other prominent carbonyl-containing lipid oxidation compounds.” Free Radical Biology and Medicine (2017). Link

Conference abstracts

Javier-Fernando Montero-Bullón, Tânia Melo, M Rosário M Domingues, Pedro Domingues “Study of covalent adduction of nitrated phospholipids to peptides using tandem mass spectrometry in different instruments” Link 

M. Rosário Domingues, Ana Campos, Simone Colombo, Tânia Melo, Pedro Domingues “Radical induced oxidation of di-oleoyl phosphatidylserine using mass spectrometry revealed preferential oxydation of Sn-2 oleoyl chain” Link 

Sofia Duarte, Álvaro Viedma-Poyatos, Andreia Mónico, Dolores Pérez-Sala “The conserved cysteine residue of type III intermediate filaments serves as a structural element and redox sensor” Link 

Andreia Mónico, Sofia Duarte, Maria A. Pajares, Dolores Pérez-Sala “Effects of oxidants and electrophiles on vimentin assembly” Link 

Bebiana C. Sousa, Corinne M. Spickett, Andrew R. Pitt. “A mass spectrometry approach for the identification and localization of acrolein modifications of proteins.” Free Radical Biology and Medicine (2017). Link

Catarina Afonso, Andrew R. Pitt, Corinne M. Spickett. “Identification and localization of protein-pentanal adducts, a potential lipoxidation marker.” Free Radical Biology and Medicine (2017). Link

Javier-Fernando Montero-Bullón, Tania Melo, Tania Martins-Marques, Henrique Girão, Rosário Domingues, Pedro Domingues. “Alteration of phospholipidome profile in the heart of an animal model of acute myocardial infarction.” Free Radical Biology and Medicine (2017). Link

Simone Colombo, Giulia Coliva, Agnieszka Kraj, Jean-Pierre Chervet, Maria Fedorova, Pedro Domingues, M. Rosario Domingues. “Oxidative metabolism of phosphatidylethanolamines predicted by electrochemistry-mass spectrometry.” Free Radical Biology and Medicine (2017). Link

M. Rosário Domingues, Tania Melo, Elisabete Maciel, Simone Colombo, Pedro Domingues. “Aminophospholipid oxidation and glycation in immunity: good or bad?.” Free Radical Biology and Medicine (2017). Link

Andreia Mónico, Silvia Zorrilla and Dolores Pérez-Sala. “Characterization of vimentin-zinc interaction and its impact on the response to electrophilic and oxidative stress.” Free Radical Biology and Medicine (2017). link

Eva Griesser, Giulia Coliva, Andreia Mónico, Dolores Pérez-Sala and Maria Fedorova “Oxidative modifications cross-talk in redox regulation of cellular physiology.” Free Radical Biology and Medicine (2017). link

Tania Melo, Sofia Duarte, Pedro Domingues, Rosario M Domingues and Dolores Pérez-Sala. “Interaction of nitrated/nitroxidized phospholipids with vimentin.” Free Radical Biology and Medicine (2017).  link

Dolores Pérez Sala. “Modification of cysteine residues by cyclopentenone prostaglandins in the elucidation of redox regulation of protein function.” Toxicology Letters (2016). link